TO DETACH, MIGRATE, ADHERE, AND METASTASIZE: CD97/ADGRE5 IN CANCER

To Detach, Migrate, Adhere, and Metastasize: CD97/ADGRE5 in Cancer

Tumorigenesis is a multistep process, during which cells acquire a series of mutations that lead to unrestrained cell growth and Dice Sets proliferation, inhibition of cell differentiation, and evasion of cell death.Growing tumors stimulate angiogenesis, providing them with nutrients and oxygen.Ultimately, tumor cells invade the surrounding tissue

read more



A systematic review assessing incorporation of prophylactic splenic artery embolisation (pSAE) into trauma guidelines for the management of high-grade splenic injury

Abstract Background Splenic artery embolisation (SAE) has become a vital strategy in the modern landscape of multidisciplinary trauma care, improving splenic salvage rates in patients with high-grade injury.However, due to a lack of prospective data there remains contention amongst stakeholders as to whether SAE should be performed at the time of p

read more