To Detach, Migrate, Adhere, and Metastasize: CD97/ADGRE5 in Cancer
Tumorigenesis is a multistep process, during which cells acquire a series of mutations that lead to unrestrained cell growth and Dice Sets proliferation, inhibition of cell differentiation, and evasion of cell death.Growing tumors stimulate angiogenesis, providing them with nutrients and oxygen.Ultimately, tumor cells invade the surrounding tissue